李言，3200威尼斯vip副研究员。2012年毕业于3200威尼斯vip食品科学与工程专业，2017年毕业于中国科学院上海生命科学研究院营养科学研究所生物化学与分子生物学专业。现为中国粮油学会食品分会理事、中国生物物理学会代谢生物学分会及运动与公共健康分会理事。2020年获中国科协第六届“青年人才托举工程”项目资助，同时主持国家自然科学基金面上项目、青年科学基金项目、省部级专项课题及企业委托项目等10余项。获3200威尼斯vip“至善青年学者”、“金龙鱼优秀教师”等荣誉称号。长期围绕营养与代谢调控以及健康食品开发方面开展基础应用研究，相关研究工作目前发表SCI论文50余篇，其中以第一作者或通讯作者在PNAS、Cell Reports、EMBO Reports、Theranostics等国际知名期刊发表论文30余篇。申报国家发明专利13项，已授权5项，申请国际专利3项。
1.国家自然科学基金委，面上项目，32071166，mTOR乳酸化修饰在骨骼肌自噬调控中的作用及机制研究，2021-01至2024-12，58万元，在研，主持
2.国家自然科学基金委，青年科学基金项目，31900841，miR-183/96在骨骼肌减少症中的作用及机制研究，2020-01至2022-12，25万元，在研，主持
3.中国科学技术协会，青年人才托举工程项目，2020QNRC001，谷物营养与代谢调控，2021-02至2023-01，45万元，在研，主持
1. Liu, J., C. Nie, L. Xue, Y. Yan, S. Liu, J. Sun, M. Fan, H. Qian, H. Ying, L. Wang＃, andY. Li＃, Growth hormone receptor disrupts glucose homeostasis via promoting and stabilizing retinol binding protein 4.Theranostics, 2021. 11(17): p. 8283-8300.
2. Wang, H., M. Ma, Y. Li, J. Liu, C. Sun, S. Liu, Y. Ma, Y. Yan, Z. Tang, S. Shen, J. Yu, Y. Wu, J. Jiang, L. Wang, Z.B. Jin, H. Ying＃, andY. Li＃, miR-183 and miR-96 orchestrate both glucose and fat utilization in skeletal muscle.EMBO Rep, 2021. 22(9): p. e52247.
3. Y. Li, J. Jiang, W. Liu, H. Wang, L. Zhao, S. Liu, P. Li, S. Zhang, C. Sun, Y. Wu, S. Yu, X. Li, H. Zhang, H. Qian, D. Zhang, F. Guo, Q. Zhai, Q. Ding, L. Wang, and H. Ying, microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle.Proc Natl Acad Sci USA, 2018. 115(46): p. E10849-E10858.
4. Zhang, K.L., J. Sun, M.C. Fan, H.F. Qian, H. Ying,Y. Li＃, and L. Wang＃, Functional ingredients present in whole-grain foods as therapeutic tools to counteract obesity: Effects on brown and white adipose tissues.Trends in Food Science & Technology, 2021. 109: p. 513-526.
5. Liu, J.X., Y. Wang, L.M. Xue, C. Nie, J. Sun, M.C. Fan, H.F. Qian, L. Wang＃, andY. Li＃, Novel Metabolic Regulation of Bile Acid Responses to Low Cholesterol in Whole-Grain-Diet-Fed Mice.Journal of Agricultural and Food Chemistry, 2021. 69(30): p. 8440-8447.
6. Yang, Z., J.Y. Mi, Y. Wang, L.M. Xue, J.X. Liu, M.C. Fan, D. Zhang, L. Wang, H.F. Qian, andY. Li＃, Effects of low-carbohydrate diet and ketogenic diet on glucose and lipid metabolism in type 2 diabetic mice.Nutrition, 2021. 89.
7. Wang, Y.C., X.H. Yao, M. Ma, H.H. Zhang, H. Wang, L. Zhao, S.N. Liu, C. Sun, P. Li, Y.T. Wu, X.H. Li, J.J. Jiang, Y.Y. Li,Y. Li＃, and H. Ying＃, miR-130b inhibits proliferation and promotes differentiation in myocytes via targeting Sp1.Journal of Molecular Cell Biology, 2021. 13(6): p. 422-432.
8. Liu, J.X.*,Y. Li*＃, C. Sun, S.N. Liu, Y. Yan, H.O. Pan, M.C. Fan, L.M. Xue, C.Z.P. Nie, H. Zhang, H.F. Qian, H. Ying, and L. Wang＃, Geniposide reduces cholesterol accumulation and increases its excretion by regulating the FXR-mediated liver-gut crosstalk of bile acids.Pharmacological Research, 2020. 152.
9. Liu, J.X.,Y. Li＃, L.M. Xue, M.C. Fan, C.P. Nie, Y. Wang, H. Zhang, H.F. Qian, and L. Wang＃, Circulating miR-27a-3p as a candidate for a biomarker of whole grain diets for lipid metabolism.Food & Function, 2020. 11(10): p. 8852-8865.
10. Nie, C.Z.P.*,Y. Li*＃, H.F. Qian, H. Ying, and L. Wang＃, Advanced glycation end products in food and their effects on intestinal tract.Critical Reviews in Food Science and Nutrition, 2020.p. 1-13.
11.Y. Li＃, H.O. Pan, J.X. Liu, T.T. Li, S.N. Liu, W.L. Shi, C. Sun, M.C. Fan, L.M. Xue, Y. Wang, C.Z.P. Nie, H. Zhang, H.F. Qian, H. Ying, and L. Wang, L-Arabinose Inhibits Colitis by Modulating Gut Microbiota in Mice.Journal of Agricultural and Food Chemistry, 2019. 67(48): p. 13299-13306.
12.Y. Li, H.O. Pan, X.T. Zhang, H. Wang, S.N. Liu, H. Zhang, H.F. Qian, L. Wang, and H. Ying, Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle.Journal of Agricultural and Food Chemistry, 2019. 67(16): p. 4483-4492.
